Form
Powder
Water Content (Karl Fisher)
≤14.0%
pH
6.0-7.0
Optical Rotation
+145° to +150°
Faropenem sodium is a broad spectrum beta-lactam antibiotic belonging to the penem antibiotic class. Faropenem sodium is freely soluble in water (>20mg/mL).
122547-49-3
C12H14NO5S • Na
335.31
β-lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to β-lactams is commonly due to cells containing plasmid encoded β-lactamases. Like other antibiotics in the penem class, faropenem sodium is highly resistant to β-lactamases and some extended spectrum β-lactamases (ESBLs).
-20°C
2941.90.5000
Faropenem sodium is a broad spectrum antibiotic and has shown to be very effective against anaerobic pathogens known to cause oral infections.
Powder
≤14.0%
6.0-7.0
+145° to +150°