Cefradine (also known as cephradine) is a first generation cephalosporin antibiotic which a has similar anti-bacterial spectrum of activity to cefalexin. Cefradine is freely soluble in aqueous solution at 21.3 mg/mL.

CAS Number

38821-53-3

Molecular Formula

C₁₆H₁₉N₃O₄S•H2O

Molecular Weight

349.40

Mechanism of Action

Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases.

Storage Conditions

-20°C

Tariff Code

2941.90.5000

Specifications: