Ceftibuten is a third generation cephalosporin antibiotic.  Ceftibuten is freely soluble in aqueous solution (70.5 mg/mL).

CAS Number

97519-39-6

Molecular Formula

C₁₅H₁₄N₄O₆S₂

Molecular Weight

410.42 g/mol

Mechanism of Action

Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases.

Storage Conditions

-20°C

Tariff Code

2941.90.5000

Spectrum

Ceftibuten is a broad spectrum antibiotic targeting a wide variety of gram positive and gram negative bacteria.

Specifications: