CapreomycinisacomplexofcyclicpentopeptidesisolatedfromStreptomycescapreolus,firstreportedin1962.Thecomplexhastwomajorcomponents,IAandIB,withanexocycliclysineresidueandtwominordelysinylcomponents,IIAandIIB.Capreomycinisapotentantibioticwithactivityagainstmycobateria,GrampositiveandGramnegativeorganisms.
Capreomycinis solublein ethanol,methanol,DMFandDMSO.
CASNumber
11003-38-6
MolecularFormula
C25H44N14O7(forIB)
MolecularWeight
652.7(forIB)
MechanismofAction
Capreomycinactsbybindingtothe23Sribosomalsubunit,disruptingproteinsynthesis.
StorageConditions
-20°C