Feglymycinisanamphoteric,13-member,linearpeptidefeaturing3,5-dihydroxyphenylalanineandaterminaldicarboxylateaminoacid,isolatedfromaStreptomycesin1999.Feglymycinisapotentantiviralagentwithantibacterialactivity,includingagainstMRSA.
Feglymycinissolubleinethanol,methanol,DMForDMSO.Poorwatersolubility.
CASNumber
209335-49-9
MolecularFormula
C95H97N13O30
MolecularWeight
1900.9
MechanismofAction
FeglymycinspecificallyinhibitstheenzymesMurAandMurCandinhibitscell-to-celltransferbetweenHIV-infectedTcells,uninfectedCD4+Tcells,andtheDC-SIGN-mediatedviraltransfertoCD4+Tcells.
StorageConditions
-20°C