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Sulfapyridine,USPisafirstgenerationsulfonamideantibioticandwasoneofthefirstcompoundsusedtotreatandcurepneumonia.Sulfapyridinehasalsobeenfoundtohaveanti-inflammatoryeffectsandcanbeusedinimmunodeficiencystudies.
TOKU-ECompanyofferstwoformsofsulfapyridine: sulfapyridine,USP(S065) and sulfapyridinesodium(S106).Inaqueoussolution,sulfapyridinesodiumisfreelysoluble(667mg/mL)whilesulfapyridineissignificantlylesssoluble(0.29mg/mL).BothformshavesimilarpotenciesandaresuitableformicroBIOLOGyuse;however,sulfapyridinesodiumiseasiertoworkwithinaqueoussolution.
144-83-2
C11H11N3O2S
249.29
Sulfapyridineinhibitsfolicacidsynthesisbyactingasacompetitiveinhibitorofdihydropteroatesynthetase,anenzymefoundinthefolicacidsynthesispathway.
2-8°C
2935.00.4200
Sulfapyridinehasabroadspectrumofactivity.
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