Cefuroxime sodium is a second generation cephalosporin antibiotic and is freely soluble in aqueous solution (0.145 mg/mL).

CAS Number

56238-63-2

Molecular Formula

C₁₆H₁₅N₄NaO₈S

Molecular Weight

446.37 g/mol

Mechanism of Action

Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases. Like many second generation cephalosporins, cefuroxime is relatively stable in the presence of β-lactamases.

Storage Conditions

-20°C

Tariff Code

2941.90.5000

Spectrum

Cefuroxime sodium is a broad spectrum antibiotic targeting a wide variety of gram negative and gram positive bacteria.

Specifications: