Clarithromycin is a macrolide antibiotic similar to erythromycin. Clarithromycin is slightly soluble in aqueous solution (0.33 µg/mL).
81103-11-9
C38H69NO13
747.95
Macrolide antibiotics inhibit bacterial growth by targeting the 50S ribosomal subunit preventing peptide bond formation and translocation during protein synthesis. Resistance to clarithromycin is commonly attributed to mutations in 50S rRNA preventing clarithromycin binding allowing the cell to synthesize proteins free of error.
Store in cool, dry conditions in well sealed containers.
2941.50.0000
Clarithromycin is a broad spectrum antibiotic targeting a wide range of gram positive and gram negative bacteria especially those which cause pharyngitis and otitis media.
Powder
White crystalline powder
Semi-synthetic
≤ 2.0%
8.0-10.0
-94° to -102°
96.0-102.0% (on dried basis)
≤ 0.2%
≤ 0.002%
Any related compound: ≤1.0%
Number of related compounds exceeding 0.4%:
≤ 4
Total Impurities: ≤ 3.5%
