PseurotinAisafungalmetabolitewithanunusualhetero-spirocyclicringsystem.IthaspotentneuritogenicactivityinPC12phaechromocytomacells,ausefulmodelforadrenergicneuronaldifferentiation.PseurotinAalsoexhibitschitinaseinhibitionandactssynergisticallywithazoleantifungalagents.
PseurotinAissolublein ethanol,methanol,DMFandDMSO.
CASNumber
58523-30-1
MolecularFormula
C22H25NO8
MolecularWeight
431.4
MechanismofAction
PseurotinAinducesmultipolarandbranchingneuritescomparabletoβ-NGF,anendogenousneurotrophicfactor.
StorageConditions
-20°C