Enrofloxacin is a fluoroquinolone antibiotic commonly used in veterinary medicine.
TOKU-E offers two forms of enrofloxacin, enrofloxacin (E016) and enrofloxacin HCl (E007). Enrofloxcin is slightly soluble in aqueous solution and enrofloxacin HCl is freely soluble at 10 mg/mL.
CAS Number
93106-60-6
Molecular Formula
C19H22FN3O3
Molecular Weight
359.39
Mechanism of Action
Fluoroquinolone antibiotics target bacterial DNA gyrase, an enzyme which reduces DNA strain during replication. Because DNA gyrase is required during DNA replication, subsequent DNA synthesis and ultimately cell division is inhibited.
Storage Conditions
2-8°C
Tariff Code
2933.59.3600
Spectrum
Enrofloxacin is a broad spectrum antibiotic targeting a wide variety of gram positive and gram negative bacteria and a few Mycoplasma species.
Form
Powder
Appearance
Light yellow or yellow-orange powder
Source
Synthetic
Impurity Profile
Impurity A| 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid||||
Impurity B| ciprofloxacin||||
Impurity C| 1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid||||
Impurity E| 6-chloro-1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid||||
Impurity F| 1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoroquinolin-4(1H)-one||||
Impurity G| 7-[(2-aminoethyl)amino]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid||||
Melting Point
221-226°C
Assay
(On Dried Basis): ≥98.5%
Loss on Drying
≤3.0%