Enrofloxacin is a fluoroquinolone antibiotic commonly used in veterinary medicine. Enrofloxcin is slightly soluble in aqueous solution and enrofloxacin HCl is freely soluble at 10 mg/mL.
CAS Number
112732-17-9
Molecular Formula
C19H22FN3O3 •HCl
Molecular Weight
395.86
Mechanism of Action
Fluoroquinolone antibiotics target bacterial DNA gyrase, an enzyme which reduces DNA strain during replication. Because DNA gyrase is required during DNA replication, subsequent DNA synthesis and ultimately cell division is inhibited.
Storage Conditions
<30°C
Tariff Code
2933.59.3600
Spectrum
Enrofloxacin is a broad spectrum antibiotic targeting a wide variety of gram positive and gram negative bacteria and a few Mycoplasma species.
Form
Powder
Appearance
Almost White Crystalline Powder
Source
Synthetic
Elemental Analysis
Fluoride: ≥4.5%
Impurity Profile
Impurity A| 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid||||
Impurity B| ciprofloxacin||||
Impurity C| 1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid||||
Impurity E| 6-chloro-1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid||||
Impurity F| 1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoroquinolin-4(1H)-one||||
Impurity G| 7-[(2-aminoethyl)amino]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid||||
pH
3.5-4.5
Assay
(On Dried Basis): ≥98.5%
Loss on Drying
≤1.0%
