Demeclocycline,achlortetracyclineanalogueproducedbyamutagenisedstrainofStreptomycesaureofaciens,wasfirstisolatedin1957.Likealltetracyclines,demeclocyclineshowsbroadspectrumantibacterialandantiprotozoanactivityandactsbybindingtothe30Sand50Sribosomalsubunits,blockingproteinsynthesis.Demeclocyclinehasbeenextensivelycitedintheliteraturewithover800referencesrelatingalmostexclusivelytoinvivouse.
Demeclocyclineissolublein ethanol,methanol,DMFandDMSO.
CASNumber
127-33-3
MolecularFormula
C21H21ClN2O8
MolecularWeight
468.9
StorageConditions
-20°C
Specifications:
Appearance
Yellowtoorangesolid