Dehydrocurvularinisa12-memberedmacrocycliclactoneincorporatingaresorcinylmoiety,producedbyanumberoffungalspeciesincludingCurvularia,PenicilliumandAlternaria.Dehydrocurvularininhibitscelldivisionbydisruptingmitoticspindleformationandactsasadevelopmentalregulatorbyinhibitingself-sporulationinAlternariaalternata.Morerecentlydehydrocurvularinhasbeenshowntohaveantimalarialactivity.
Dehydrocurvularinissolublein ethanol,methanol,DMFandDMSO.
CASNumber
1095588-70-7
MolecularFormula
C16H18O5
MolecularWeight
290.3
StorageConditions
-20°C
Specifications:
Appearance
Whitetooffwhitesolid