Metronidazoleisanitromidazoleantibioticusedspecificallyagainstanaerobicbacteria. Inaqueoussolution,metronidazoleissparinglysolubleat<10mg/mL.
CASNumber
443-48-1
MolecularFormula
C6H9N3O3
MolecularWeight
171.15g/mol
MechanismofAction
Inanaerobiccells,metronidazolemetabolitesformunstablemoleculeswhichareincorporatedintocellularDNAultimatelyinhibitingDNAreplicationandtranscription.Thisuniquemechanismhasabactericidaleffectonanaerobiccells.
StorageConditions
2-8°C
TariffCode
2933.29.4500
Spectrum
MetronidazoleismostlyusedtocombatanaerobicbacteriaincludingClostridiumdifficileandBacteroidesfragilis.
Form
Powder
Appearance
Whiteoryellowishcrystallinepowder
Source
Synthetic
ImpurityProfile
Anyimpurity:Notmorethan0.1%
Totalimpurities:Notmorethan0.2%
MeltingPoint
159-163°C
LossonDrying
<0.5%
SulfatedAsh
Notmorethan0.1%
HeavyMetals
Notmorethan20ppm
ResidualSolvents
Methyleneoxide:Notmorethan0.15ppm
Formicacid:Notmorethan124ppm