Metronidazole is a nitromidazole antibiotic used specifically against anaerobic bacteria. In aqueous solution, metronidazole is sparingly soluble at <10 mg/mL.
443-48-1
C6H9N3O3
171.15 g/mol
In anaerobic cells, metronidazole metabolites form unstable molecules which are incorporated into cellular DNA ultimately inhibiting DNA replication and transcription. This unique mechanism has a bactericidal effect on anaerobic cells.
2-8°C
2933.29.4500
Metronidazole is mostly used to combat anaerobic bacteria including Clostridium difficile and Bacteroides fragilis.
Powder
White or yellowish crystalline powder
Synthetic
Any impurity: Not more than 0.1%
Total impurities: Not more than 0.2%
159-163°C
<0.5%
Not more than 0.1%
Not more than 20ppm
Methylene oxide: Not more than 0.15 ppm
Formic acid: Not more than 124 ppm
