Demeclocyclinehydrochlorideisasaltpreparedfromdemeclocyclinetakingadvantageofthebasicdimethylaminogroupwhichprotonatesandre
lyformsasaltinhydrochloricacidsolutions.Thehydrochlorideisthepreferredformulationforpharmaceuticalapplications.Likealltetracyclines,demeclocyclineshowsbroadspectrumantibacterialandantiprotozoanactivity.
Demeclocyclinehydrochlorideissolublein ethanol,methanol,DMF,DMSO,andwater.
CASNumber
64-73-3
MolecularFormula
C21H22Cl2N2O8
MolecularWeight
501.3
MechanismofAction
DemeclocyclineHClblocksproteinsynthesisbybindingtothe30Sand50Sribosomalsubunits.
StorageConditions
-20°C