Form

Powder

Appearance

Whitecrystallinepowder

Source

Synthetic

ImpurityProfile

ImpurityA|(RS)-9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid(FPA);OfloxacinDifluoroCarboxylicAcid|82419-35-0|C₁₃H₉F₂NO₄|281.21|ImpurityB|(RS)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-2,3-dihydro-7H-pyrido-[1,2,3-de]-1,4-benzoxazin-7-one||||ImpurityE|(RS)-9-Fluoro-3-methyl-7-oxo-10-(piperazin-1-yl)-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicAcid;N-DesmethylOfloxacinHCl|82419-52-1|C₁₇H₁₈FN₃O₄|347.34|ImpurityF|4-[(RS)-6-Carboxy-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-10-yl]-1-methylpiperazine1-OxideHydrochloride(OfloxacinN-OxideAcetateSalt)|104721-52-0|C₂₀H₂₄FN₃O₇|437.42||OfloxacinR-Isomer;(+)-(R)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid;(R)-(+)-Ofloxacin;D-Ofloxacin;LevofloxacinR-Isome|100986-86-5|C₁₈H₂₀FN₃O₄|361.37|

MeltingPoint

250-257°C

OpticalRotation

-1°to+1°

Assay

(OnDriedBasis):98.5-101.5%

LossonDrying

≤0.2%