Sulfathiazole sodium is a bacteriostatic sulfonamide antibiotic. Sulfathiazole acts as a competitor with para-aminobenzoic acid (PABA) in the folic acid synthesis pathway. Sulfathiazole sodium is sparingly soluble in aqueous solution 0.373 mg/mL.
CAS Number
144-74-1
Molecular Formula
C9H8N3NaO2S2
Molecular Weight
277.30 g/mol
Mechanism of Action
Sulfonamide will be catalyzed to competitive combine with the pteridine in stead of the PABA in synthesis of folic acid, inhibiting production of folic acid.
Storage Conditions
<30°C, protected from light
Tariff Code
2935.00.3300
Spectrum
Sulfathiazole is a broad spectrum antibiotic targeting a wide range of gram positive and gram negative bacteria.
Form
Powder
Appearance
White or yellowish crystalline powder
Impurity Profile
Related substances: Not more than 0.5%
pH
(1% in water) 9.0 - 10.0
Density
Not less than 0.5 g/cm3
Assay
(On dried basis): 99.0% - 101.0%
Loss on Drying
6.0 - 10.0%
Heavy Metals
Not more than 20ppm