Form
Powder
Appearance
Whiteoroffwhitepowder
Source
Synthetic
ImpurityProfile
IndividualImpurity:≤3.0%
TotalImpurities:≤10.0%
Cis-isomer:82.0-88.0%
Trans-isomer:12.0-18.0%
WaterContent(KarlFisher)
≤5.0%
Assay
(OnDriedBasis):≥85.0%
Tilmicosinisaslighltysolublesemisyntheticmacrolideantibiotic.
108050-54-0
C46H80N2O13
869.13
Macrolideantibioticsinhibitbacterialgrowthbytargetingthe50Sribosomalsubunitpreventingpeptidebondformationandtranslocationduringproteinsynthesis.Resistancetotilmicosiniscommonlyattributedtomutationsin50SrRNApreventingtilmicosinbindingallowingthecelltosynthesizeproteinsfreeoferror.
2-8°C
2933.39.6190
Tilmicosinprimarilytargetsgramnegativebacteriaespeciallythosewhichcausebovinerespiratorydisease.
Powder
Whiteoroffwhitepowder
Synthetic
IndividualImpurity:≤3.0%
TotalImpurities:≤10.0%
Cis-isomer:82.0-88.0%
Trans-isomer:12.0-18.0%
≤5.0%
(OnDriedBasis):≥85.0%