A54556AisanunusualdepsipeptideisolatedfromStreptomyceshawaiiensisbyresearchersatEliLillyin1985,featuringatrienonesidechain.A54556AispotentlyactiveagainstGrampositiveandGramnegativebacteria,includingMRSA.ADEPsareconsideredimportantleadsinthedevelopmentofnewgenerationsofantibioticsagainstresistantbacteria.
A54556Aissolublein ethanol,methanol,DMFandDMSO.
CASNumber
95398-45-1
MolecularFormula
C38H50N6O8
MolecularWeight
718.8
MechanismofAction
A54556Aactsbyactivatinganddis-regulatingClp-familyproteins.
StorageConditions
-20°C