A 54556A is an unusual depsipeptide isolated from Streptomyces hawaiiensis by researchers at Eli Lilly in 1985, featuring a trienone side chain. A 54556A is potently active against Gram positive and Gram negative bacteria, including MRSA. ADEPs are considered important leads in the development of new generations of antibiotics against resistant bacteria.
A 54556A is soluble in ethanol, methanol, DMF and DMSO.
CAS Number
95398-45-1
Molecular Formula
C38H50N6O8
Molecular Weight
718.8
Mechanism of Action
A 54556A acts by activating and dis-regulating Clp-family proteins.
Storage Conditions
-20°C