TyrocidineisafamilyofeightcationiccyclicdecapeptidesproducedbyBacillusbrevis,firstreportedbyDubosin1941.TyrocidinesexhibitbroadantibioticactivityagainstGrampositiveandnegativebacteriaandarethemajorcomponentofthetyrothricincomplexwhichisusedfortreatmentoftopicalinfections.
CASNumber
8011-61-8
MolecularFormula
C66H87N13O13(forTyrocidineA)
MolecularWeight
1269.7
MechanismofAction
Themechanismofactionoftyrocidinesisnotfullyunderstood;however,theyareknowntoactbydisturbinglipidbilayersofthebacterialcellmembrane.
StorageConditions
-20°C