Virginiamycin S1 is one of a family of depsipeptide antibiotics co-produced with ostreogrycin A and used as a synergistic mixture. Virginiamycin S1, also known as Staphylomycin S and Factor S among other synonyms, was discovered independently and named by several groups, leading to considerable confusion in the literature. Virginiamycin S1 differs from virginiamycin B in lacking the dimethylamino moiety on the phenyl ring.
Virginiamycin S1 is soluble in ethanol, methanol, DMF and DMSO.
CAS Number
23152-29-6
Molecular Formula
C43H49N7O10
Molecular Weight
823.9
Mechanism of Action
Virginiamycin S1 acts a synergist, binding to the conformational change of the peptidyl transferase centre of the 50S ribosome induced by ostreogrycin A.
Storage Conditions
-20°C