VirginiamycinS1isoneofafamilyofdepsipeptideantibioticsco-producedwithostreogrycinAandusedasasynergisticmixture.VirginiamycinS1,alsoknownasStaphylomycinSandFactorSamongothersynonyms,wasdiscoveredindependentlyandnamedbyseveralgroups,le
ngtoconsiderableconfusionintheliterature.VirginiamycinS1differsfromvirginiamycinBinlackingthedimethylaminomoietyonthephenylring.
VirginiamycinS1issolubleinethanol,methanol,DMFandDMSO.
CASNumber
23152-29-6
MolecularFormula
C43H49N7O10
MolecularWeight
823.9
MechanismofAction
VirginiamycinS1actsasynergist,bindingtotheconformationalchangeofthepeptidyltransferasecentreofthe50SribosomeinducedbyostreogrycinA.
StorageConditions
-20°C