Platencin is a novel, broad spectrum, Gram-positive antibiotic produced by strains of Streptomyces platensis. Platencin is more potent than its analogue, platensimycin. Platencin shows potent in vivo efficacy without any observed toxicity. Platencin targets two essential proteins, b-ketoacyl-acyl carrier protein (ACP) synthase II (FabF) and III (FabH) whereas platensimycin targets only FabF.
Platencin is soluble in ethanol, methanol, DMF and DMSO.
CAS Number
869898-86-2
Molecular Formula
C24H27NO6
Molecular Weight
425.2
Storage Conditions
-20°C
Specifications:
Appearance
Light tan solid