AlamethicinF50isaneutrallinearpeptaibolcomplexwithpotentantibioticactivity,containing20"aminoacids"withacetylandphenylalaninoltermini,producedbyTrichodermasp..AlamethicinF50isco-producedwithanacidiclinearpeptaibolcomplex(alamethicinF30).Alamethicinitselfisavariablemixtureoftheacidicandneutralcomponents.Ingeneral,reportsonalamethicindonotspecifytheratioofF50toF30inthecomplexandcomparativedatabetweenthecomplexesisscant.
CASNumber
56165-93-6
MolecularFormula
C92H151N23O24
MolecularWeight
1963.4
MechanismofAction
AlamethicinF50actsanionopohore,transportingionsthroughmembranesandartificiallipidmembranes.AlamethicinF50formsvoltage-dependentionchannelsinlipidbilayermembranes.
StorageConditions
-20°C