Ionomycin was isolated from Streptomyces conglobatus as a potent Gram positive antibiotic. During isolation, it was recognised that ionomycin exhibits a very high affinity and selectivity for calcium ions, suggesting the metabolite acts as a calcium ionophore. More recently, ionomycin has been used in cell biology as a universal calcium ionophore to explore the role of calcium regulation in the cell.
Ionomycin is soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
CAS Number
56092-81-0
Molecular Formula
C41H72O9
Molecular Weight
709.0
Storage Conditions
-20°C
Specifications: