Corynecin III (methamphenicol) is a member of a naturally-occurring complex of chloramphenicol-like acyl nitrophenylpropylamines isolated from Corynebacterium hydrocarboclastus in 1972. Corynecin III is active against Gram positive and Gram negative bacteria. Although less potent than chloramphenicol, corynecin III shows a similar species selectivity. Corynecin III was used as a bioisostere of chloroamphenicol to examine the binding relationship of chloramphenicols to DraE virulence factor.
Corynecin III is soluble in ethanol, methanol, DMF and DMSO.
CAS Number
18048-95-8
Molecular Formula
C13H18N2O5
Molecular Weight
282.3
Storage Conditions
-20°C
Specifications: