icindoleproducedbyseveralspeciesofAspergillusandPenicillium.CyclopiazonicacidisahighlyspecificinhibitorofcalciumATPaseofsarcoplasmicreticulum,alteringcalciumhomeostasisandATP-dependentcalciumtransportandresultinginthereleaseofintracellularstoredCa2+withoutincreasingIP3.
CASNumber
18172-33-3
MolecularFormula
C20H20N2O3
MolecularWeight
336.4
MechanismofAction
CyclopiazonicacidisahighlyspecificinhibitorofcalciumATPaseofsarcoplasmicreticulum,alteringcalciumhomeostasisandATP-dependentcalciumtransportandresultinginthereleaseofintracellularstoredCa2+withoutincreasingIP3.
StorageConditions
-20°C