Davercin(erythromycinAcyclic11,12-carbonate)isafirstgenerationsemi-syntheticerythromycin.Davercinispreparedbycouplingthe11-and12-OHgroupstoformacycliccarbonate.Thissimplemodificationimprovesthest
ABIlityandhydrophobicityofthemacrocyclicstructure.Davercinshowscomparableorbetterinvitropotency,lowhosttoxicityandimprovedpharmacokineticscomparedwitherythromycin.
Davercinissolublein ethanol,methanol,DMFandDMSO.
CASNumber
55224-05-0
MolecularFormula
C38H65NO14
MolecularWeight
759.9
StorageConditions
-20°C
Specifications: